1. . Consider the following types of substitution mutations. Make a table describing the DNA mutation, the effects on the protein and the possible effects

1. . Consider the following types of substitution mutations. Make a table describing the DNA mutation, the effects on the protein and the possible effects on the cell: transition, transversion, missense, nonsense, neutral, silent and frameshift Consider a protein that has the following sequence of amino acid.  This is the wild type protein sequence. Met – Thr – Cys – His – Ser – Ser … Mutations of the DNA have led to the following protein sequences.  In each case, provide an explanation of a mutation or mutations that are most likely to have could have occurred.  Discuss how these mutations will effect the cell. a.  Met –  Thr – Ser – His – Ser – Ser … b.  Met – Thr c.  Met – Thr – Leu– Ser – Phe – Phe …… Codons for the same amino acid tend to differ only by the third base position.  Why?

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